Germline Alterations of Tumor Susceptibility Genes in New York Cancer Patients

NAActive, not recruitingINTERVENTIONAL
Enrollment

21,081

Participants

Timeline

Start Date

March 31, 2000

Primary Completion Date

March 31, 2026

Study Completion Date

March 31, 2026

Conditions
Breast CancerBladder CancerKidney CancerColon CancerProstate CancerLung CancerOvarian Cancer
Interventions
GENETIC

PCR/PCR/LDR Strategy

Evaluate the extent to which polymorphisms in BRCA1, BRCA2, PTEN, T β R1, TGF β-1, DNA repair genes (including ATM and CHK2), APC, ER, PR, MCP-1, MPIF, CCR2/5 and CCR3 are correlated with cancer incidence. Candidate genes will also be selected from 1) cytokine signaling and 2) apoptosis regulatory pathways.

Trial Locations (1)

10065

Memorial Sloan Kettering Cancer Center, New York

All Listed Sponsors
collaborator

Columbia University

OTHER

collaborator

Weill Medical College of Cornell University

OTHER

collaborator

Icahn School of Medicine at Mount Sinai

OTHER

lead

Memorial Sloan Kettering Cancer Center

OTHER

NCT00579514 - Germline Alterations of Tumor Susceptibility Genes in New York Cancer Patients | Biotech Hunter | Biotech Hunter