Safety and Efficacy Study of Recombinant Human Insulin-Like Growth Factor-I/Recombinant Human Insulin-Like Growth Factor Binding Protein-3 (rhIGF-I/rhIGFBP-3) In Myotonic Dystrophy Type 1

PHASE2CompletedINTERVENTIONAL
Enrollment

69

Participants

Timeline

Start Date

December 31, 2007

Primary Completion Date

December 29, 2008

Study Completion Date

December 29, 2008

Conditions
Myotonic Dystrophy Type 1
Interventions
DRUG

rhIGF-I/rhIGFBP-3

1.0 mg/kg rhIGF-I/rhIGFBP-3 or placebo daily, subcutaneous injections from baseline through the last day of the end of study visit.

DRUG

placebo

1.0 mg/kg rhIGF-I/rhIGFBP-3 or placebo daily, subcutaneous injections from baseline through the last day of the end of study visit.

Trial Locations (12)

14642

University of Rochester, Neuromuscular Disease Center, Rochester

21287

Johns Hopkins Hospital, Baltimore

43210

Ohio State University Medical Center, Columbus

55455

University of Minnesota, Minneapolis

63110

Washington University Medical School, St Louis

66160

University of Kansas Medical Center, Kansas City

78229

University of Texas Health Science Center, San Antonio

84112

University of Utah, Salt Lake City

92868

University of California Irvine Medical Center; MDA, ALS and Neuromuscular Center, Orange

95817

University of California, Davis, Sacramento

97239

Oregan Health and Science University, Portland

77555-0539

Universit of Texas Medical Branch, Galveston

All Listed Sponsors
collaborator

Muscular Dystrophy Association

OTHER

lead

Insmed Incorporated

INDUSTRY

NCT00577577 - Safety and Efficacy Study of Recombinant Human Insulin-Like Growth Factor-I/Recombinant Human Insulin-Like Growth Factor Binding Protein-3 (rhIGF-I/rhIGFBP-3) In Myotonic Dystrophy Type 1 | Biotech Hunter | Biotech Hunter