Extrapleural Pneumonectomy /Pleurectomy Decortication, IHOC Cisplatin and Gemcitabine With Amifostine and Sodium Thiosulfate Cytoprotection for Resectable Malignant Pleural Mesothelioma

Resection of the lung, the lining of the lung (pleura), the covering of the heart (pericardium), and the muscle that separates the chest and abdomen (diaphragm)

Given after the tumor is removed as a bath (perfusion) for one-hour

Given after the tumor is removed as a bath (perfusion) for one-hour

Given intravenously before perfusion chemotherapy and then 2 hours after the first dose

Given intravenously immediately at the end of perfusion chemotherapy

Resection of the lining of the lung (pleura), while the lung remains intact.