The Effect of Valproate on Benzodiazepine Withdrawal Severity

NACompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

February 28, 2005

Primary Completion Date

May 31, 2008

Study Completion Date

May 31, 2008

Conditions
Substance Withdrawal Syndrome
Interventions
DRUG

valproate

Valproate 20 mg/kg per day for 2 weeks, reduction during week 3. Conversion of benzodiazepines to an equivalent dose of diazepam (maximum 80 mg per day). Dosage reduced 10 mg daily until 40 mg per day. Reduction then continued 5 mg daily.

Trial Locations (1)

09

Helsinki University Central Hospital, Department of Psychiatry, Psychiatric Unit for Drug Dependence, Helsinki

All Listed Sponsors
lead

University of Helsinki

OTHER

NCT00570219 - The Effect of Valproate on Benzodiazepine Withdrawal Severity | Biotech Hunter | Biotech Hunter