ELND005 in Patients With Mild to Moderate Alzheimer's Disease

PHASE2CompletedINTERVENTIONAL
Enrollment

353

Participants

Timeline

Start Date

December 31, 2007

Primary Completion Date

May 31, 2010

Study Completion Date

May 31, 2010

Conditions
Alzheimer Disease
Interventions
DRUG

Placebo Control

ELND005 matched placebo capsules for oral administration, bid for 78 weeks

DRUG

ELND005

ELND005 capsules for oral administration at a dose of 2000 mg bid for 78 weeks

DRUG

ELND005

ELND005 capsules for oral administration at a dose of 250 mg bid for 78 weeks

DRUG

ELND005

ELND005 capsules for oral administration at a dose of 1000 mg bid for 78 weeks

Trial Locations (62)

10029

Mount Sinai Medical Center, New York

10032

Columbia University Sergievsky Center, New York

12205

Upstate Clinical Research, LLC, Albany

12208

Neurological Associates of Albany, PC, Albany

14620

AD-CARE, Monroe Community Hospital, Rochester

15213

University of Pittsburgh Alzheimer Disease Research Clinic, Pittsburgh

19001

Abington Neurological Associates, Inc., Abington

19046

The Clinical Trial Center, LLC, Jenkintown

20057

Georgetown University Medical Center, Dept. of Neurology, Washington D.C.

22903

University of Virginia Health System, Charlottesville

27607

Raleigh Neurology Associates, Raleigh

29615

Alliance for Neuro Research, LLC dba Absher Neurology, PA, Greenville

30033

Dekalb Neurology Associates, LLC, Decatur

30329

Emory University, Dept. of Neurology, Atlanta

32806

Compass Research, LLC, Orlando

33021

Sunrise Clinical Research, Inc, Hollywood

33137

Miami Jewish Home and Hospital For The Aged, Miami

33173

Avision Research Associates, LLC, Miami

33351

Neurology Clinical Research, Inc., Sunrise

33407

Premiere Research Institute, West Palm Beach

33445

Brain Matters Research, Inc., Delray Beach

33617

University of South Florida Suncoast Alzheimer's and Gerontology Center, Tampa

34243

Roskamp Institute, Sarasota

42003

Innovative Clinical Concepts, Paducah

43623

Neurology & Neuroscience Center of Ohio, Toledo

46202

Department of Neurology - Indiana University Medical Center, Indianapolis

48109

University of Michigan, Taubman Health Care Center, Dept. of Neurology, Ann Arbor

66160

University of Kansas Medical Center, Department of Neurology, Kansas City

78229

Radiant Research San Antonio, San Antonio

84108

University of Utah, Dept. of Neurology, Salt Lake City

85006

Banner Alzheimer's Institute, Phoenix

85351

Sun Health Research Institute, Sun City

85724

University of Arizona, Health Sciences Center, Dept. of Neurology, Tucson

87109

Albuquerque Neuroscience, Inc., Albuquerque

89102

University of Nevada School of Medicine, Las Vegas

90095

UCLA Alzheimer's Disease Center, Dept. of Neurology, Los Angeles

92845

Collaborative NeuroScience Network, Inc., Garden Grove

92868

UC Irvine Medical Center, Orange

93720

Margolin Brain Institute, Fresno

94143

UCSF Medical Center, Dept. of Neurology, San Francisco

97210

Summit Research Newtwork, Inc., Portland

97504

Medford Neurological and Spine Clinic, Medford

06510

Yale University School of Medicine, Alzheimer's Disease Research Unit, New Haven

02115

Brigham and Women's Hospital, Dept. of Neurology, Boston

08009

Comprehensive Clinical Research, Berlin

07724

The Memory Enhancement Center of America, Inc., Eatontown

08540

Global Medical Institutes, Princeton

02906

Butler Hospital, Memory and Aging Center, Providence

05201

Clinical Neuroscience Research Associates, Inc-The Memory Clinic, Bennington

05405

University of Vermont Medical Center, Fletcher Allen Health Care, Dept. of Neurology, Burlington

T5G 0B7

Glenrose Rehabilitation Hospital, Edmonton

V6T 2B5

University of British Columbia Hospital, Division of Neurology, Vancouver

K7L 5G2

Hotel Dieu Hospital, Kingston

N6A 4V2

Saint Joseph's Health Care London, Saint Joseph's Hospital, Dept. of Cognitive Neurology, London

N6C 5J1

Parkwood Hospital, London

K1N 5C8

Sisters of Charity of Ottawa Health Service, Ottawa

K9H 2P4

Kawartha Regional Memory Clinic, Peterborough

M3B 2S7

Toronto Memory Program, Toronto

M5T 2S8

Whitby Mental Health Memory Clinic, Toronto

M6M 3Z5

Gerontion Research, Inc., Toronto

J4V 2J2

Neuro-Rive-Sud Memory Clinic, Greenfield Park

H1T 2M4

Recherche Clinique de Neurologie (Hospital Maisonneuve Rosemont), Montreal

All Listed Sponsors
lead

OPKO Health, Inc.

INDUSTRY

NCT00568776 - ELND005 in Patients With Mild to Moderate Alzheimer's Disease | Biotech Hunter | Biotech Hunter