834
Participants
Start Date
March 31, 2008
Primary Completion Date
May 31, 2011
Study Completion Date
May 31, 2011
Etanercept
Subcutaneous (SC), 50 mg, once weekly for 88 weeks
Methotrexate
"Oral, 15 to 25 mg (varying based on dosage the subject is receiving at the time of screening and may be increased at the discretion of the investigator through Week 28 to a maximum of 25 mg/week), once weekly for 88 weeks.~If a subject experiences an adverse event (AE) during the study, Methotrexate may be decreased by 2.5 or 5.0 mg weekly (the minimum dose to stay in the study is 10 mg/week)."
Etanercept
Subcutaneous (SC), 25 mg, once weekly from week 36 to week 88.
Methotrexate
"Oral, 15 to 25 mg (varying based on dosage the subject is receiving at the time of screening and may be increased at the discretion of the investigator through Week 28 to a maximum of 25 mg/week), once weekly for 88 weeks.~If a subject experiences an adverse event (AE) during the study, Methotrexate may be decreased by 2.5 or 5.0 mg weekly (the minimum dose to stay in the study is 10 mg/week)."
Placebo
Subcutaneous (SC), once weekly from week 36 to week 88.
Methotrexate
"Oral, 15 to 25 mg (varying based on dosage the subject is receiving at the time of screening and may be increased at the discretion of the investigator through Week 28 to a maximum of 25 mg/week), once weekly for 88 weeks.~If a subject experiences an adverse event (AE) during the study, Methotrexate may be decreased by 2.5 or 5.0 mg weekly (the minimum dose to stay in the study is 10 mg/week)."
Pfizer Investigational Site, Tapei City
Pfizer Investigational Site, Kaohsiung City
Pfizer Investigational Site, Budapest
Pfizer Investigational Site, Vienna
Pfizer Investigational Site, Brussels
Pfizer Investigational Site, Campsie
Pfizer Investigational Site, Kogarah
Pfizer Investigational Site, Heidelberg West
Pfizer Investigational Site, Malvern
Pfizer Investigational Site, Liège
Pfizer Investigational Site, Debrecen
Pfizer Investigational Site, Leipzig
Pfizer Investigational Site, Maroochydore
Pfizer Investigational Site, Daw Park
Pfizer Investigational Site, Yvoir
Pfizer Investigational Site, Victoria Park
Pfizer Investigational Site, Szombathely
Pfizer Investigational Site, Orbassano
Pfizer Investigational Site, Berlin
Pfizer Investigational Site, Belgrade
Pfizer Investigational Site, Mexico City
Pfizer Investigational Site, A Coruña
Pfizer Investigational Site, Niska Banja
Pfizer Investigational Site, Eilbek
Pfizer Investigational Site, Málaga
Pfizer Investigational Site, Toulouse
Pfizer Investigational Site, Oskarström
Pfizer Investigational Site, Montpellier
Pfizer Investigational Site, Seville
Pfizer Investigational Site, Guadalajara
Pfizer Investigational Site, Cologne
Pfizer Investigational Site, Monterrey
Pfizer Investigational Site, Strasbourg
Pfizer Investigational Site, Le Mans
Pfizer Investigational Site, Paris
Pfizer Investigational Site, Querétaro
Pfizer Investigational Site, Falun
Pfizer Investigational Site, Bruntál
Pfizer Investigational Site, Bruntál
Pfizer Investigational Site, Corbeil-Essonnes
Pfizer Investigational Site, Le Kremlin-Bicêtre
Pfizer Investigational Site, Catania
Pfizer Investigational Site, Mérida
Pfizer Investigational Site, Würzburg
Pfizer Investigational Site, Moscow
Pfizer Investigational Site, Moscow
Pfizer Investigational Site, Moscow
Pfizer Investigational Site, Saint Petersburg
Pfizer Investigational Site, Saint Petersburg
Pfizer Investigational Site, Santiago
Pfizer Investigational Site, Barranquilla
Pfizer Investigational Site, Bogota
Pfizer Investigational Site, Warsaw
Pfizer Investigational Site, Moscow
Pfizer Investigational Site, Zlín
Pfizer Investigational Site, Brno
Pfizer Investigational Site, Bruntál
Pfizer Investigational Site, Prague
Pfizer Investigational Site, Prague
Pfizer Investigational Site, Nice
Pfizer Investigational Site, Leipzig
Pfizer Investigational Site, Debrecen
Pfizer Investigational Site, Roma
Pfizer Investigational Site, Mexico City
Pfizer Investigational Site, Heerlen
Pfizer Investigational Site, Bydgoszcz
Pfizer Investigational Site, Lodz
Pfizer Investigational Site, Lublin
Pfizer Investigational Site, Szczecin
Pfizer Investigational Site, Seo-gu
Pfizer Investigational Site, Namdong-gu
Pfizer Investigational Site, Seoul
Pfizer Investigational Site, Seongdong-gu
Pfizer Investigational Site, Anyang-si Gyeonggi-do
Pfizer Investigational Site, Seoul
Pfizer Investigational Site, Seoul
Pfizer Investigational Site, Santiago de Compostela
Pfizer Investigational Site, Barcelona
Pfizer Investigational Site, Sabadell
Pfizer Investigational Site, Wigan
Pfizer Investigational Site, Dudley
Lead Sponsor
Pfizer
INDUSTRY