Safety Study of a Genetically Modified Adenovirus in Ovarian Cancer Patients

PHASE1CompletedINTERVENTIONAL
Enrollment

26

Participants

Timeline

Start Date

June 30, 2007

Primary Completion Date

May 31, 2009

Study Completion Date

June 30, 2010

Conditions
Ovarian CancerPrimary Peritoneal Cancer
Interventions
PROCEDURE

Tenckhoff Catheter placement

'Tenckhoff catheter' will be placed into the abdominal cavity by a minor surgical procedure performed in the Radiology Department.

DRUG

Ad5-delta24RGD

"Within two weeks before the start of the study, a physical exam, blood tests, removal of fluid from abdominal cavity through the catheter and a CT scan of abdomen and pelvis will be performed.~The procedure will involve receiving the Ad5-delta24RGD virus once a day for 3 days. The virus will be put into the abdominal cavity through a 'Tenckhoff catheter'."

Trial Locations (1)

35205

UAB Highlands, 1201 11th Ave S, 4th Floor, Gynecologic Oncology, Birmingham

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

University of Alabama at Birmingham

OTHER

NCT00562003 - Safety Study of a Genetically Modified Adenovirus in Ovarian Cancer Patients | Biotech Hunter | Biotech Hunter