Comparison of Three Drug Combinations for Intermittent Treatment of Malaria in Children

PHASE2/PHASE3CompletedINTERVENTIONAL
Enrollment

1,295

Participants

Timeline

Start Date

August 31, 2007

Primary Completion Date

February 29, 2008

Study Completion Date

June 30, 2008

Conditions
Malaria
Interventions
DRUG

SP, amodiaquine, piperaquine, dihdroartemisinin

once every month during september, October and November

DRUG

intermittent preventive treatment

SP(500mg sulfadoxine/25mg pyrimethamine)1.25mg SP per kg stat Amodiaquine (200mg base) 25mg/kg over 3 days Piperaquine (320 mg per tablet) 16.8 g/kg daily for 3 days Du-Cotecxin ( 40mg dihydroartemisinin(DHA)/320mg piperaquine(PQP))PQP/DHA 1.6/12.8mg/kg once daily for 3 days

DRUG

Du-Cotecxin

Du-Cotecxin (40mg dihydroartemisinin (DHA/320mg Piperaquine (PQP) PQP/DHA 1.6/12.8mg/kg once daily for 3 days

Trial Locations (1)

Unknown

Medical Research Council Laboratories,, Banjul

All Listed Sponsors
collaborator

Department of State for Health and Social Welfare, The Gambia

OTHER_GOV

lead

London School of Hygiene and Tropical Medicine

OTHER

NCT00561899 - Comparison of Three Drug Combinations for Intermittent Treatment of Malaria in Children | Biotech Hunter | Biotech Hunter