Comparison of Autologous Chondrocyte Implantation Versus Mosaicoplasty: a Randomized Trial

PHASE3CompletedINTERVENTIONAL
Enrollment

58

Participants

Timeline

Start Date

April 30, 2007

Primary Completion Date

October 31, 2012

Study Completion Date

August 31, 2013

Conditions
Knee Chondral or Osteochondral Defect
Interventions
PROCEDURE

Autologous chondrocytes transplantation

Cartilage was harvested, then transferred for cell isolation and culture. Cells are suspended in agarose and transferred to cylindrical molds and surgically implanted 4 weeks later.

PROCEDURE

Mosaicoplasty

Osteochondral patch are sampled and then implanted during the same surgical procedure

Trial Locations (12)

29200

Orthopaedic surgery Departement Brest University Hospital, Brest

69300

CHU de Lyon, Lyon

14 033

CHU de Caen, Caen

71 640

Centre médico chirurgical de Dracy-Le-Fort, Dracy-le-Fort

38 042

CHU de Grenoble, Grenoble

78 150

Ch Versailles, Le Chesnay

87 000

Clinique Chenieux, Limoges

53 103

CH Nord Mayenne, Mayenne

54 035

CHU de Nancy, Nancy

94 160

HIA Bégin, Saint-Mandé

67 400

CHU de Strasbourg, Strasbourg

Unknown

Clinique du cours Dillon, Toulouse

All Listed Sponsors
collaborator

Institut National de la Santé Et de la Recherche Médicale, France

OTHER_GOV

lead

University Hospital, Brest

OTHER

NCT00560664 - Comparison of Autologous Chondrocyte Implantation Versus Mosaicoplasty: a Randomized Trial | Biotech Hunter | Biotech Hunter