Safety Study of Oxaliplatin and 5-fluorouracil Followed by FUDR for Unresectable Colorectal Liver Metastases

PHASE1CompletedINTERVENTIONAL
Enrollment

14

Participants

Timeline

Start Date

July 31, 2007

Primary Completion Date

March 31, 2012

Study Completion Date

August 31, 2014

Conditions
Colorectal Liver Metastases
Interventions
DRUG

Drug: 5-FU

Dose escalation (200 to 900 mg/m²) scheme, one hour isolated hepatic perfusion prior to standard treatment.

DRUG

Drug: Oxaliplatin

40 mg/m², one hour isolated hepatic perfusion prior to standard treatment.

Trial Locations (1)

15232

UPMC Cancer Centers Network, Pittsburgh

All Listed Sponsors
collaborator

National Institutes of Health (NIH)

NIH

collaborator

National Cancer Institute (NCI)

NIH

lead

David Bartlett

OTHER

NCT00557557 - Safety Study of Oxaliplatin and 5-fluorouracil Followed by FUDR for Unresectable Colorectal Liver Metastases | Biotech Hunter | Biotech Hunter