Continuous Positive Airway Pressure for Acute Pulmonary Edema

PHASE3CompletedINTERVENTIONAL
Enrollment

208

Participants

Timeline

Start Date

October 31, 2004

Primary Completion Date

July 31, 2008

Study Completion Date

July 31, 2008

Conditions
Pulmonary EdemaDyspneaParoxysmalCongestive Heart Failure
Interventions
PROCEDURE

Continuous Positive Airway Pressure (CPAP)

"Usual treatment of acute pulmonary oedema (see arm A) + CPAP will be administered without interruption for at least one hour and will be stopped for efficacy:~stade I or II KILLIP classification and FR less or equal to 25 /min and SpO2 larger than 90 % ambient air and patient willing the stop of CPAP because of improvement of his clinical status."

PROCEDURE

usual care of acute pulmonary oedema

"Usual treatment of acute pulmonary oedema including :~Oxygen, diuretic minimum one bolus IV of 40 mg FUROSEMIDE (LASILIX) possibility to repeat the dose every 15 minutes with a maximum 120 mg.~Bolus of ISOSORBIDE DINITRATE (RISORDAN) of 1 mg maybe repeated every 3 minutes.~As soon as possible perfusion of ISDN with flow adapted to the clinical status If necessary administration of DOBUTAMINE continuous perfusion of to 5 to 20 µg/kg/min."

Trial Locations (1)

75010

DUCROS Laurent, Paris

All Listed Sponsors
lead

Assistance Publique - Hôpitaux de Paris

OTHER

NCT00554580 - Continuous Positive Airway Pressure for Acute Pulmonary Edema | Biotech Hunter | Biotech Hunter