Phase II Study to Evaluate the Combination of Rituximab and DepoCyte® in the C5R Chemotherapy Protocol in Patients Between the Ages of 18 and 60 Years With Primary Cerebral Non-Hodgkin Lymphoma and Systemic Diffuse Large B-cell Lymphoma With Neuromeningeal Invasion at Diagnosis

PHASE2CompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

July 31, 2007

Primary Completion Date

June 30, 2012

Study Completion Date

March 31, 2017

Conditions
Lymphoma, Non-HodgkinDiffuse Large B-cell Lymphoma
Interventions
DRUG

Rituximab

375 mg/m2 D1

DRUG

Cytarabine

50 mg D3

Trial Locations (46)

1090

AZ VUB, Jette

1200

UCL- Saint Luc, Brussels

1340

Clinique Saint Pierre, Ottignies

2060

ZNA Stuivenberg, Antwerp

4000

CHR de la Citadelle, Liège

5530

UCL - Mont-Godinne, Yvoir

6000

CH Notre Dame, Charleroi

6110

CHU Charleroi-Vésale, Montigny-le-Tilleul

8000

A. Z. Sint-Jan, Bruges

8800

Heilig Hart Ziekenhuis, Roeselare

Bruges

Hôpital Saint Joseph, Arlon

F-74011

CH d'Annecy, Annecy

F-84902

Centre Hospitalier d'Avignon, Avignon

F-64100

Hôpital de Bayonne, Bayonne

F-93009

Hôpital d'Avicenne, Bobigny

F-33300

Polyclinique Bordeaux Nord Aquitaine, Bordeaux

F-19190

CH de Brive, Brive-la-Gaillarde

F-14033

CHU Clemenceau, Caen

F-14076

Centre Francois Baclesse, Caen

F-73011

CH de Chambery, Chambéry

F-28018

CH de Chartres, Chartres

F-91108

Hôpital Gilles de Corbeil, Corbeil-Essonnes

F-94010

Hôpital Henri Mondor, Créteil

F-21034

CHU Le Bocage, Dijon

F-59385

Centre Hospitalier de Dunkerque, Dunkirk

F-17019

Hôpital Saint Louis, La Rochelle

F-78157

Hôpital Andre Mignot, Le Chesnay

F-94270

Hôpital Bicêtre, Le Kremlin-Bicêtre

F-62307

CHU de Lens, Lens

F-59020

Hopital Saint Vincent de Paul, Lille

F-59037

CHU Claude Huriez, Lille

F-87000

Hôpital Dupuytren, Limoges

F-69373

Centre Leon Berard, Lyon

F-71018

Hôpital des Chanaux, Mâcon

F-77100

CH de Meaux, Meaux

F-57038

Hôpital Bon Secours, Metz

F-68070

Hôpital Emile Muller, Mulhouse

F-06054

Centre Antoine Lacassagne, Nice

F-75475

Hôpital Saint Louis, Paris

F-75743

Hôpital Necker, Paris

F-66046

Centre Hospitalier de Perpigan, Perpignan

F-69495

Centre Hospitalier Lyon Sud, Pierre-Bénite

F-76038

Centre Henri Becquerel, Rouen

F-78108

CH de St Germain, Saint-Germain-en-Laye

F-31000

Hôpital Purpan, Toulouse

Unknown

Hopital Brabois, Vandœuvre-lès-Nancy

All Listed Sponsors
lead

Lymphoma Study Association

OTHER

NCT00553943 - Phase II Study to Evaluate the Combination of Rituximab and DepoCyte® in the C5R Chemotherapy Protocol in Patients Between the Ages of 18 and 60 Years With Primary Cerebral Non-Hodgkin Lymphoma and Systemic Diffuse Large B-cell Lymphoma With Neuromeningeal Invasion at Diagnosis | Biotech Hunter | Biotech Hunter