Albumin-bound Paclitaxel (ABI-007) for Patients With Advanced Non-Small Cell Lung Cancer

PHASE3CompletedINTERVENTIONAL
Enrollment

1,052

Participants

Timeline

Start Date

November 1, 2007

Primary Completion Date

October 1, 2009

Study Completion Date

February 1, 2013

Conditions
Non-Small Cell Lung Carcinoma
Interventions
DRUG

Albumin-bound paclitaxel

Administered by intravenous infusion.

DRUG

Paclitaxel

Administered by intravenous infusion.

DRUG

Carboplatin

Administered by intravenous infusion. Dosing was based on the Calvert formula: carboplatin dose (mg) = (Target AUC) x (glomerular filtration rate \[GFR\] + 25). For the purposes of this protocol, the GFR is considered to be equivalent to creatinine clearance (calculated by the method of Cockcroft and Gault, 1976).

Trial Locations (37)

13326

Mary Imogene Bassett Hospital, Cooperstown

19047

St. Mary Medical Center- Oncology, Hematology PC, Langhorne

21202

Mercy Medical Center, Baltimore

24211

Cancer Outreach Associates, PC, Abingdon

27599

University of North Carolina at Chapel Hill, Chapel Hill

29425

Medical University of South Carolina, Charleston

31701

Phoebe Cancer Center, Albany

32778

Lake County Oncology and Hematology, PA, Tavares

33705

Gulf Coast Oncology Associates, St. Petersburg

35805

Clearview Cancer Institute Oncology Specialties, P.C., Huntsville

40202

Kentuckiana Cancer Institute, PLLC, Louisville

63110

St. Louis University, St Louis

67214

Cancer Center of Kansas, Wichita

71913

Genesis Cancer Center- Hot Springs, Hot Springs

72205

Little Rock Hematology Oncology Associates, Little Rock

75137

Dallas Oncology Consultants, PA, Duncanville

75701

Blood and Cancer Center of East Texas, Tyler

Tyler Hematology Oncology, Tyler

76104

The Center for Cancers and Blood Disorders, Fort Worth

79410

Joe Arrington Cancer Research and Treatment Center, Lubbock

90813

Pacific Shores Medical Group, Long Beach

92064

Southwest Cancer Care, Escondido

92262

Comprehensice Cancer Ctr., Palms Springs

92708

Robert A. Moss, MD, FACP, Inc., Fountain Valley

92801

Pacific Cancer Medical Center, Inc., Anaheim

93030

Ventura County Hematology-Oncology Specialists, Oxnard

93309

Comprehensive Blood and Cancer Center, Bakersfield

04101

Mercy Hospital, Portland

04074

Maine Center for Cancer Medicine, Scarborough

07109

Essex Oncology of North Jersey, Belleville

05405

Fletcher Allen Health Care, Burlington

V3L 3W4

Royal Columbian Hospital, New Westminster

L6R 3J7

William Osler Health Centre, Brampton Clinic, Brampton

M4C3E7

Toronto East General Hospital, Toronto

M5G 2M9

Princess Margaret Hospital, Toronto

H2W 1S6

McGill University- Dept. of Oncology, Montreal

H4J 1C5

Hopital du Sacre-Coeur de Montreal, Montreal

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Celgene

INDUSTRY

NCT00540514 - Albumin-bound Paclitaxel (ABI-007) for Patients With Advanced Non-Small Cell Lung Cancer | Biotech Hunter | Biotech Hunter