A Study of the Onset and Offset of Antiplatelet Effects Comparing Ticagrelor, Clopidogrel, and Placebo With Aspirin

Oral, 90 mg; 180 mg loading dose followed by 90 mg twice daily (BD)

Oral 75 mg; 600 mg loading dose followed by 75 mg once daily (ODD)

Oral, 75 mg to 100 mg once daily. Aspirin obtained locally by the investigator, according to local practice. The dose remained constant throughout the study.