245
Participants
Start Date
August 31, 2007
Primary Completion Date
July 31, 2011
Study Completion Date
March 31, 2012
escitalopram
10mg/d increasing by 10 mg/week to a maximum of 40 mg/d if tolerated and not remitted
bupropion extra long (XL)
150mg/d increasing to 300 mg/d after 1 week and 450 mg/d after 3 weeks, all increases if tolerated and not remitted
escitalopram + bupropion
same dosing schedule as for monotherapy
New York State Psychiatric Institute, New York
University of Ottawa, Institute of Mental Health Research, Ottawa
University of Ottawa
OTHER
National Institute of Mental Health (NIMH)
NIH
New York State Psychiatric Institute
OTHER