Everolimus in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma

PHASE2CompletedINTERVENTIONAL
Enrollment

35

Participants

Timeline

Start Date

August 31, 2007

Primary Completion Date

January 31, 2010

Study Completion Date

August 31, 2012

Conditions
Lymphoma
Interventions
DRUG

everolimus

Patients receive oral everolimus once daily on days 1-28. Treatment repeats every 28 days for up to 6 courses in the absence of disease progression or unacceptable toxicity.

GENETIC

molecular response by PCR

Bone marrow and peripheral blood samples are collected periodically and analyzed for molecular response by PCR. Molecular studies are also performed on DNA level formalin-fixed paraffin-embedded tissue

Trial Locations (21)

6500

Istituto Oncologico della Svizzera Italiana, Bellinzona

8002

Onkozentrum - Klinik im Park, Zurich

20141

European Institute of Oncology, Milan

33604

Hopital Haut Leveque, Pessac

37044

Centre Hospitalier Universitaire Bretonneau de Tours, Tours

38043

CHU de Grenoble - Hopital de la Tronche, Grenoble

40138

University of Bologna Medical School, Bologna

F-94805

Institut Gustave Roussy, Villejuif

CH-5001

Hirslanden Klinik Aarau, Aarau

CH-5404

Kantonsspital Baden, Baden

CH-4031

Universitaetsspital-Basel, Basel

CH-3010

Inselspital Bern, Bern

CH-7000

Kantonsspital Graubuenden, Chur

CH-1011

Centre Hospitalier Universitaire Vaudois, Lausanne

CH-4600

Kantonsspital Olten, Olten

CH-9007

Kantonsspital - St. Gallen, Sankt Gallen

CH-1226

Hopitaux Universitaires de Geneve, Thonex-Geneve

CH-8400

Kantonsspital Winterthur, Winterthur

CH-8032

Klinik Hirslanden, Zurich

CH-8063

City Hospital Triemli, Zurich

CH-8091

UniversitaetsSpital Zuerich, Zurich

All Listed Sponsors
lead

Swiss Cancer Institute

OTHER

NCT00516412 - Everolimus in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma | Biotech Hunter | Biotech Hunter