Effect of Sodium Bicarbonate Solution in Decreasing the Incidence of Contrast Induced Nephropathy (CIN)

PHASE3CompletedINTERVENTIONAL
Enrollment

265

Participants

Timeline

Start Date

August 31, 2007

Primary Completion Date

June 30, 2008

Study Completion Date

June 30, 2008

Conditions
Contrast Induced Nephropathy
Interventions
DRUG

Sodium Bicarbonate plus normal saline 0.9%

IV sodium bicarbonate 8.4% solved in 154 mEq/ L NaCl 0.9% (infused at the rate of 3 ml/kg/ hour one hour before the angiographic procedure, continuing at the rate of 1 ml/kg/ hour for 6 hours after the procedure. Maximum rate of fluid permitted is that for a body weight of 110 Kg.

DRUG

normal saline 0.9%

IV 154 mEq/L solution of NaCl 0.9% (infused at the rate of 3 ml/kg/ hour one hour before the angiographic procedure, continuing at the rate of 1 ml/kg/ hour for 6 hours after the procedure. Maximum rate of fluid permitted is that for a body weight of 110 Kg.)

Trial Locations (1)

1411713138

Tehran Heart Center, Tehran

All Listed Sponsors
collaborator

Tehran Heart Center

OTHER

lead

Tehran University of Medical Sciences

OTHER

NCT00514150 - Effect of Sodium Bicarbonate Solution in Decreasing the Incidence of Contrast Induced Nephropathy (CIN) | Biotech Hunter | Biotech Hunter