Rituxan With or Without Methotrexate in Psoriatic Arthritis

PHASE1CompletedINTERVENTIONAL
Enrollment

6

Participants

Timeline

Start Date

December 31, 2006

Primary Completion Date

January 31, 2010

Study Completion Date

March 31, 2010

Conditions
Psoriatic Arthritis
Interventions
DRUG

Rituximab

1000mg (1gm) given as an IV infusion every two weeks for 2 doses (days 1 and 15). The first infusion of rituximab should be administered IV at an initial rate of 50 mg/hr. If a hypersensitivity or infusion related reaction does not occur, escalate the infusion rate by 50 mg/hr increments every 30 minutes, to a maximum of 400 mg/hr.

Trial Locations (4)

14642

University of Rochester, Rochester

98104

Swedish Rheumatology Research, Seattle

92037-0943

University of California, San Diego, La Jolla

94305-5350

Stanford University, Stanford

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Genentech, Inc.

INDUSTRY

lead

Swedish Medical Center

OTHER