646
Participants
Start Date
December 8, 2005
Primary Completion Date
December 18, 2019
Study Completion Date
December 18, 2019
Bupropion
Starting dose 150 mg by mouth daily (150 mg every morning for three days; 150 mg twice a day thereafter)
Varenicline
Starting dose 0.5 mg by mouth daily (0.5 mg every morning for days 1 - 3, then 0.5 mg twice a day for days 4 - 7, then 1 mg twice a day thereafter)
Placebo
Placebo by mouth for 12 weeks.
Smoking Cessation Counseling
Counseling over 8 months and telephone support calls.
University of Texas MD Anderson Cancer Center, Houston
National Institutes of Health (NIH)
NIH
National Institute on Drug Abuse (NIDA)
NIH
M.D. Anderson Cancer Center
OTHER