NCT00506155View on ClinicalTrials.gov

Neoadjuvant Chemotherapy With Methotrexate, Vinblastine, Adriamycin and Cisplatin (M-VAC) Plus Avastin in Patients With Urothelial Cancer

PHASE2CompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

June 30, 2007

Primary Completion Date

August 31, 2014

Study Completion Date

August 31, 2014

Conditions
Bladder Cancer
Interventions
DRUG

Avastin

10 mg/kg by vein over 90 minutes

DRUG

Cisplatin

70 mg/m\^2 by vein over 4 hours

DRUG

Doxorubicin

30 mg/m\^2 by vein over 15 minutes

DRUG

Methotrexate

30 mg/m\^2 by vein over 30 minutes

DRUG

Vinblastine Sulfate

3 mg/m\^2 by vein over 30 minutes

Trial Locations (1)

77030

UT MD Anderson Cancer Center, Houston

Sponsors

Collaborators (1)

Genentech, Inc.
All Listed Sponsors
collaborator

Genentech, Inc.

INDUSTRY

lead

M.D. Anderson Cancer Center

OTHER