A Comparison of Dexmedetomidine and Haloperidol in Patients With Intensive Care Unit (ICU)-Associated Agitation and Delirium

PHASE2CompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

January 31, 2005

Primary Completion Date

November 30, 2008

Study Completion Date

November 30, 2008

Conditions
DeliriumAgitationVentilator WeaningRespiration, ArtificialIntensive Care
Interventions
DRUG

dexmedetomidine

Dexmedetomidine IV infusion of 0.0 to 0.7 mg/kg/min for as long a deemed necessary by the treating clinician.

DRUG

haloperidol

Haloperidol IV loading dose of 2.5mg, followed by a continuous infusion of 0.0 to 2mg/hr for as long as deemed necessary by the treating clinician

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

The Alfred

OTHER

lead

Austin Health

OTHER_GOV