Naltrexone and Varenicline: Weight Gain and Tolerability in Cigarette Smokers

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

July 31, 2007

Primary Completion Date

June 30, 2009

Study Completion Date

June 30, 2009

Conditions
SmokingNicotine Dependence
Interventions
DRUG

Naltrexone

Varenicline (Chantix) 1 mg oral tablet twice per day + naltrexone 25 mg oral capsule once per day

DRUG

Varenicline

Arm 1 (Experimental) = Varenicline (Chantix) 1 mg oral tablet twice per day + naltrexone 25 mg oral capsule once per day; Arm 2 (Placebo Comparator) = Varenicline (Chantix) 1 mg oral tablet twice per day + placebo naltrexone 25 mg oral capsule once per day

Trial Locations (1)

06511

Yale University School of Medicine Substance Abuse Treatment Unit, New Haven

All Listed Sponsors
collaborator

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NIH

collaborator

National Institute on Drug Abuse (NIDA)

NIH

lead

Yale University

OTHER

NCT00502216 - Naltrexone and Varenicline: Weight Gain and Tolerability in Cigarette Smokers | Biotech Hunter | Biotech Hunter