NCT00496665 - ZD6474 (Zactima) and Metronomic Chemotherapy in Advanced Breast Cancer | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

July 31, 2007

Primary Completion Date

August 31, 2008

Study Completion Date

March 31, 2009

Conditions

Metastatic Breast Cancer

Interventions

DRUG

Vandetanib

Taken orally once a day in 28-day cycles (the dose will vary)

DRUG

Cyclophosphamide

Metronic Chemotherapy: Low dose pills taken every day of each 28-day cycle

DRUG

Methotrexate

Metronic Chemotherapy: low dose pills taken on days 1 and 2 of each week

Trial Locations (2)

Dana-Farber Cancer Institute, Boston

Massachusetts General Hospital, Boston