570
Participants
Start Date
December 31, 2007
Primary Completion Date
April 30, 2011
Study Completion Date
April 30, 2011
Nevirapine based therapy
"* Patients below 60 kg: 1 tablet twice a day of Triomune30®, including NVP 200 mg, 3TC 150 mg and D4T 30mg~* Patients above 60kg: 1 tablet twice a day of Triomune40®, including NVP 200 mg, 3TC 150 mg and D4T 40 mg)"
Efavirenz based therapy
Efavirenz EFV 200 mg (3 tablets/d) Lamivudine 3TC 300mg (2 tablets of 150mg/d) D4T generic 30mg or 40mg (2 tablets/d)
Rifampicin (RMP) Ethambutol (E) Isoniazid (H) Pyrazinamid (Z)
"* Intensive phase: 2 months daily E(RMP)HZ. PTB smear positive patients at month 2 will receive 1 more month intensive phase.~* Continuation phase: 4 months daily H(RMP).~* Patients with meningitis will receive Streptomycin instead of E during intensive phase."
Health centre of Alto Mae, Chamanculo district, Maputo
Health centre of Josue Macao, Maputo
Health centre of Malavane, Maputo
Medecins Sans Frontieres, Netherlands
OTHER
French National Agency for Research on AIDS and Viral Hepatitis
OTHER_GOV