Hepatic Arterial Infusion With Floxuridine and Dexamethasone Combined With Combination Chemotherapy in Treating Patients With Colorectal Cancer That Has Spread to the Liver

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

64

Participants

Timeline

Start Date

May 31, 2007

Primary Completion Date

May 31, 2026

Study Completion Date

May 31, 2026

Conditions
Colorectal CancerMetastatic Cancer
Interventions
DRUG

dexamethasone

Given by hepatic arterial infusion

DRUG

floxuridine

Given by hepatic arterial infusion

DRUG

fluorouracil

Given IV

DRUG

irinotecan hydrochloride

Given IV

DRUG

leucovorin calcium

Given IV

DRUG

oxaliplatin

Given IV

Trial Locations (5)

10065

Memorial Sloan Kettering Cancer Center, New York

11725

Memorial Sloan Kettering Cancer Center @ Suffolk, Commack

Unknown

Memorial Sloan Kettering Cancer Center, Basking Ridge

Memorial Sloan Kettering at Mercy Medical Center, Rockville Centre

Memorial Sloan Kettering Cancer Center@Phelps Memorial Hospital, Sleepy Hollow

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Memorial Sloan Kettering Cancer Center

OTHER