Glutamate for Metabolic Intervention in Coronary Surgery

PHASE3CompletedINTERVENTIONAL
Enrollment

865

Participants

Timeline

Start Date

October 31, 2005

Primary Completion Date

December 31, 2009

Study Completion Date

August 31, 2022

Conditions
Coronary Artery BypassMyocardial IschemiaMyocardial InfarctionCoronary Artery Disease
Interventions
DRUG

Intravenous infusion of saline

Intravenous infusion of isotonic saline at a rate of 1.65 ml/hour and kg body weight beginning with institution of anesthesia and stopping 2 hours after unclamping of aorta in patients operated for unstable coronary artery disease.

OTHER

Intravenous glutamate infusion

Intravenous infusion of 0.125 M glutamic acid solution at a rate of 1.65 ml/hour and kg body weight beginning with institution of anesthesia and stopping 2 hours after unclamping of aorta in patients operated for unstable coronary artery disease.

Trial Locations (3)

SE-371 85

Blekingesjukhuset, Karlskrona, Karlskrona

SE-581 85

University Hospital, Linköping, Linköping

SE 701 85

University Hospital, Örebro, Örebro

All Listed Sponsors
collaborator

Region Örebro County

OTHER

collaborator

Blekingesjukhuset, Karlskrona

UNKNOWN

lead

University Hospital, Linkoeping

OTHER

NCT00489827 - Glutamate for Metabolic Intervention in Coronary Surgery | Biotech Hunter | Biotech Hunter