Study Evaluating Safety, Tolerability, And Immunogenicity Of ACC-001 In Subjects With Mild To Moderate Alzheimer's Disease

PHASE2CompletedINTERVENTIONAL
Enrollment

86

Participants

Timeline

Start Date

May 31, 2007

Primary Completion Date

January 31, 2013

Study Completion Date

January 31, 2013

Conditions
Alzheimer Disease
Interventions
BIOLOGICAL

ACC-001 + QS-21

Vanutide Cridificar (3, 10, 30µg) + QS-21 (50µg), IM on day 1, month 1, month 3, month 6 and month 12

BIOLOGICAL

ACC-001

Vanutide Cridificar (10, 30µg), IM on day 1, month 1, month 3, month 6 and month 12

BIOLOGICAL

QS-21

QS-21 (50µg), IM on day 1, month 1, month 3, month 6 and month 12

DRUG

Placebo: Phosphate buffered saline

Phosphate buffered Saline (pH : 7.4), IM on day 1, month 1, month 3, month 6 and month 12

Trial Locations (24)

13385

Hôpital Sainte-Marguerite, Marseille

14050

Klinik fuer Psychiatrie und Psychotherapie, Charite Universitaetsmedizin Berlin, Berlin

28040

Hospital Universitario Clinico San Carlos, Madrid

31059

Hôpital LA GRAVE, Toulouse

31240

Clinique de L'Union, St.-Jean

31300

Chru Purpan, Toulouse

Clinique PASTEUR, Toulouse

33076

Hopital Pellegrin-Centre Mémoire de Recherche et de Ressources, Bordeaux

34295

CHU Hôpital Gui de Chaulliac, Montpellier

37075

Klinik fuer Psychiatrie und Psychotherapie, Göttingen

48149

Universitaetsklinikum Muenster, Münster

48165

Universitaetsklinikum Muenster, Münster

59037

CHRU de Lille, Lille

CHRU de Lille, Lille (mri)

67227

Zentralinstitut fuer Seelische Gesundheit, Frankenthal

68159

Zentralinstitut fuer Seelische Gesundheit, Mannheim

75013

Groupe Hospitalier Broca-La Rochefoucauld, Paris

75651

Groupe Hospitalier Pitie-Salpetriere, Paris

Hôpital Pitié-Salpétrière, Paris

79106

Unversitätsklinikum Freiburg, Freiburg im Breisgau

81675

Technische Universitaet Muenchen, Klinikum rechts der Isar, München

08003

Hospital del Mar, Barcelona

08025

Hospital de la Santa Creu i Sant Pau, Barcelona

08036

Hospital Clinico y Provincial, Barcelona

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Janssen Alzheimer Immunotherapy (JAI) Research and Development, LLC

UNKNOWN

lead

Pfizer

INDUSTRY