Thymoglobulin and Total Lymphoid Irradiation for Hematologic Malignancies

NACompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

June 30, 2006

Primary Completion Date

May 31, 2009

Study Completion Date

May 31, 2009

Conditions
LymphomaLeukemia
Interventions
DRUG

Thymoglobulin

1.5 mg/kg by vein on Days -11 to -7.

RADIATION

Total Lymphoid Irradiation

80 cGy daily on days -11 to -7 and -4 to 0.

PROCEDURE

Peripheral Blood Stem Cell Infusion

PBSC infusion administered on day 0.

DRUG

Rituximab

375 mg/m\^2 by vein on days -13, -6, 1, \& 8. Only those patients whose tumors express CD20 will receive Rituximab.

Trial Locations (1)

77030

U.T.M.D. Anderson Cancer Center, Houston

All Listed Sponsors
collaborator

Genzyme, a Sanofi Company

INDUSTRY

lead

M.D. Anderson Cancer Center

OTHER

NCT00476229 - Thymoglobulin and Total Lymphoid Irradiation for Hematologic Malignancies | Biotech Hunter | Biotech Hunter