Study of Cobimetinib in Participants With Solid Tumors

PHASE1CompletedINTERVENTIONAL
Enrollment

119

Participants

Timeline

Start Date

May 31, 2007

Primary Completion Date

April 30, 2014

Study Completion Date

April 30, 2014

Conditions
Solid Tumor
Interventions
DRUG

cobimetinib

Repeating oral dose

DRUG

dextromethorphan

In Stage III only: single dose of dextromethorphan

DRUG

midazolam

In Stage III only: single dose of midazolam

Trial Locations (4)

14263

Buffalo

48201

Detroit

90095

Los Angeles

94305-5821

Stanford

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Genentech, Inc.

INDUSTRY