Erlotinib and Bevacizumab in Treating Patients With Stage IV Melanoma

PHASE2CompletedINTERVENTIONAL
Enrollment

34

Participants

Timeline

Start Date

September 30, 2004

Primary Completion Date

August 31, 2008

Study Completion Date

September 30, 2008

Conditions
Melanoma
Interventions
BIOLOGICAL

bevacizumab

10mg/kg, slow IV infusion, Days 1 and 14

DRUG

erlotinib hydrochloride

150mg PO qd

GENETIC

fluorescence in situ hybridization

Targeting multiple genetic aberrations in isolated tumor cells.

GENETIC

gene expression analysis

gene expression analysis

OTHER

immunologic technique

immunologic technique

OTHER

laboratory biomarker analysis

laboratory biomarker analysis

PROCEDURE

biopsy

biopsy

Trial Locations (4)

37067

Vanderbilt-Ingram Cancer Center at Franklin, Nashville

37203

Sarah Cannon Research Institute, Nashville

37067-1631

Vanderbilt-Ingram Cancer Center - Cool Springs, Nashville

37232-6838

Vanderbilt-Ingram Cancer Center, Nashville

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Vanderbilt-Ingram Cancer Center

OTHER

NCT00466687 - Erlotinib and Bevacizumab in Treating Patients With Stage IV Melanoma | Biotech Hunter | Biotech Hunter