Phase 1 Study of EZN-2968 Weekly in Adult Patients With Advanced Solid Tumors or Lymphoma

PHASE1CompletedINTERVENTIONAL
Enrollment

52

Participants

Timeline

Start Date

March 31, 2007

Primary Completion Date

June 30, 2011

Study Completion Date

June 30, 2011

Conditions
CarcinomaLymphoma
Interventions
DRUG

Intravenous EZN-2968 (anti-HIF-1α LNA AS-ODN)

IV infusion of EZN 2968 given in 6 week cycles for (3 weeks on 3 weeks off) until recommended phase 2 dose identified. Up to 3 intensification cohorts will receive the recommended Phase 2 dose of EZN-2968.

Trial Locations (3)

27710

Duke University Medical Center, Durham

79410

Joe Arrington Cancer Research and Treatment Center, Lubbock

19111-2497

Fox Chase Cancer Center, Philadelphia

Sponsors
All Listed Sponsors
lead

Enzon Pharmaceuticals, Inc.

INDUSTRY