Safety of and Immune Response to a Meningitis Vaccine in HIV-Infected Children and Youth

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

384

Participants

Timeline

Start Date

June 30, 2007

Primary Completion Date

March 31, 2013

Study Completion Date

March 31, 2013

Conditions
HIV InfectionsMeningitis
Interventions
BIOLOGICAL

Quadrivalent meningococcal conjugate vaccine

MCV4 vaccine (4 µg each of meningococcal A, C, Y, and W-135 polysaccharides conjugated to approximately 48 µg of diphtheria toxoid protein carrier ) was given by injection intramuscularly at least once and no more than three times for each participant, depending on adverse reactions.

Trial Locations (37)

10016

Nyu Ny Nichd Crs, New York

10029

Metropolitan Hosp. NICHD CRS, New York

10032

Columbia IMPAACT CRS, New York

10457

Bronx-Lebanon CRS, The Bronx

10461

Jacobi Med. Ctr. Bronx NICHD CRS, The Bronx

11794

SUNY Stony Brook NICHD CRS, Stony Brook

14642

Strong Memorial Hospital Rochester NY NICHD CRS, Rochester

19104

The Children's Hosp. of Philadelphia IMPAACT CRS, Philadelphia

20010

Children's National Med. Ctr. Washington DC NICHD CRS, Washington D.C.

20060

Howard Univ. Washington DC NICHD CRS, Washington D.C.

21201

Univ. of Maryland Baltimore NICHD CRS, Baltimore

27710

DUMC Ped. CRS, Durham

32209

Univ. of Florida Jacksonville NICHD CRS, Jacksonville

33136

Pediatric Perinatal HIV Clinical Trials Unit CRS, Miami

33316

South Florida CDTC Ft Lauderdale NICHD CRS, Fort Lauderdale

33606

USF - Tampa NICHD CRS, Tampa

38105

St. Jude Children's Research Hospital CRS, Memphis

48201

Children's Hospital of Michigan NICHD CRS, Detroit

60612

Rush Univ. Cook County Hosp. Chicago NICHD CRS, Chicago

60614

Ann & Robert H. Lurie Children's Hospital of Chicago (LCH) CRS, Chicago

70112

Tulane Univ. New Orleans NICHD CRS, New Orleans

77030

Texas Children's Hospital CRS, Houston

80045

Univ. of Colorado Denver NICHD CRS, Aurora

90502

Harbor UCLA Medical Ctr. NICHD CRS, Torrance

90806

Miller Children's Hosp. Long Beach CA NICHD CRS, Long Beach

91803

Usc La Nichd Crs, Alhambra

92103

University of California, UC San Diego CRS, San Diego

94143

Univ. of California San Francisco NICHD CRS, San Francisco

98105

Seattle Children's Research Institute CRS, Seattle

90027-6062

Children's Hospital of Los Angeles NICHD CRS, Los Angeles

90095-1752

UCLA-Los Angeles/Brazil AIDS Consortium (LABAC) CRS, Los Angeles

02115

Children's Hosp. of Boston NICHD CRS, Boston

02118

Boston Medical Center Ped. HIV Program NICHD CRS, Boston

01605

WNE Maternal Pediatric Adolescent AIDS CRS, Worcester

07103

Rutgers - New Jersey Medical School CRS, Newark

00935

University of Puerto Rico Pediatric HIV/AIDS Research Program CRS, San Juan

00936

San Juan City Hosp. PR NICHD CRS, San Juan

All Listed Sponsors
collaborator

International Maternal Pediatric Adolescent AIDS Clinical Trials Group

NETWORK

lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

NCT00459316 - Safety of and Immune Response to a Meningitis Vaccine in HIV-Infected Children and Youth | Biotech Hunter | Biotech Hunter