Treatment of B-Chronic Lymphocytic Leukemia (B-CLL) With Autologous CD40 Ligand and IL-2-Expressing Tumor Cells

PHASE1CompletedINTERVENTIONAL
Enrollment

6

Participants

Timeline

Start Date

December 31, 2006

Primary Completion Date

October 31, 2008

Study Completion Date

August 31, 2013

Conditions
Chronic Lymphocytic Leukemia (CLL)
Interventions
BIOLOGICAL

CD40 LIGAND AND IL-2-EXPRESSING TUMOR CELLS VACCINE

Patients will receive a fixed dose (2 x 10\^7) of IL-2 secreting B-cells together with (2 x 10\^7)hCD40L expressing B-cells. They will receive 18 deltoid injections over 52 weeks.

Trial Locations (1)

77030

The Methodist Hospital, Houston

All Listed Sponsors
collaborator

The Methodist Hospital Research Institute

OTHER

collaborator

Center for Cell and Gene Therapy, Baylor College of Medicine

OTHER

lead

Baylor College of Medicine

OTHER

NCT00458679 - Treatment of B-Chronic Lymphocytic Leukemia (B-CLL) With Autologous CD40 Ligand and IL-2-Expressing Tumor Cells | Biotech Hunter | Biotech Hunter