36
Participants
Start Date
August 31, 2007
Primary Completion Date
March 31, 2015
Study Completion Date
June 30, 2016
Campath 1H
10, 9, 8, 7, and 6 days before transplant subjects will be given 1 dose of campath 1H given via catheter (0.2 mg/kg over 2 hours).
Cyclophosphamide
7 days before the transplant, 1 dose of cyclophosphamide is given via catheter (50mg/kg IV over 2 hours).
Fludarabine
6, 5, 4, 3, and 2 days before the transplant, 1 dose fludarabine is given via catheter (40 mg/kg IV over 1 hour)
Total Body Irradiation
1 day before the transplant one dose (200 cGy) of total body irradiation is given
Stem Cell Transplantation
Infusion of stem cells on Day 0.
antithymocyte globulin
ATG (rabbit) 3 mg/kg for 3 days.
Methylprednisolone
2mg/kg IV is given before each dose of antithymocyte globulin (ATG).
Masonic Cancer Center, University of Minnesota, Minneapolis
Masonic Cancer Center, University of Minnesota
OTHER