Reduced Intensity Stem Cell Transplantation for Chronic Lymphocytic Leukemia Followed by Vaccination

PHASE1CompletedINTERVENTIONAL
Enrollment

27

Participants

Timeline

Start Date

February 28, 2007

Primary Completion Date

February 28, 2014

Study Completion Date

April 30, 2020

Conditions
Chronic Lymphocytic Leukemia
Interventions
BIOLOGICAL

GM-K562 vaccine

The vaccine will be administered over 1 cycle of 7 weeks, that begins 1 month after stem cell transplant. The vaccine will be given 6 times over 2 months -- once a week for three weeks then every other week for 3 vaccines.

PROCEDURE

stem cell transplantation

Participants will be admitted to the hospital for approximately 8 days to receive chemotherapy and stem cell transplantation

Trial Locations (1)

02115

Dana-Farber Cancer Institute, Boston

All Listed Sponsors
collaborator

Brigham and Women's Hospital

OTHER

lead

Dana-Farber Cancer Institute

OTHER

NCT00442130 - Reduced Intensity Stem Cell Transplantation for Chronic Lymphocytic Leukemia Followed by Vaccination | Biotech Hunter | Biotech Hunter