351
Participants
Start Date
June 25, 2007
Primary Completion Date
September 30, 2009
Study Completion Date
March 31, 2010
Dietary Portfolio - Intensive
Dietitians advised participants to consume the following therapeutic diet components (\<7% of energy saturated fat, \<200 mg/d cholesterol) plus the combination of viscous fibers, soy protein, plant sterols and nuts. The portfolio diet plan will include foods which contribute 9.8 g/1000 kcal viscous fiber as B-glucan (oats, barley, oat bran breads and soups) and psylliium (cereal), 0.94 g plant sterol/1000 kcal diet (in sterol margarine), 22.5 g soy protein/1000 kcal (soy burgers, dogs, links, other meat analogues, milks, yogurts and cheese) and 22.5 g nuts/1000 kcal as part of a low fat vegetarian diet. Participants received 7 visits during a 6-month period with the study dietitian.
Dietary Portfolio - Routine
Dietitians advised participants to consume the following therapeutic diet components (\<7% of energy saturated fat, \<200 mg/d cholesterol) plus the combination of viscous fibers, soy protein, plant sterols and nuts. The portfolio diet plan will include foods which contribute 9.8 g/1000 kcal viscous fiber as B-glucan (oats, barley, oat bran breads and soups) and psylliium (cereal), 0.94 g plant sterol/1000 kcal diet (in sterol margarine), 22.5 g soy protein/1000 kcal (soy burgers, dogs, links, other meat analogues, milks, yogurts and cheese) and 22.5 g nuts/1000 kcal as part of a low fat vegetarian diet. Participants received 2 visits during a 6-month period with the study dietitian.
Control (low saturated fat therapeutic diet)
Dietitians advised participants to consume the following therapeutic diet components (\<7% of energy saturated fat, \<200 mg/d cholesterol) with a focus on low-fat dairy and whole grain cereals together with fruit and vegetables as part of a low fat vegetarian diet, and avoidance of the specific portfolio components.
Healthy Heart Program, St. Paul's Hospital, Vancouver
Richardson Centre for Functional Foods and Nutraceuticals, University of Manitoba, Winnipeg
Sunnybrook Health Sciences Centre, Toronto
St. Michael's Hospital, Toronto
Institute on Nutraceuticals and Functional Foods and the Lipid Research Center, Laval University Hospital Research Center, Québec
Canadian Institutes of Health Research (CIHR)
OTHER_GOV
Loblaw Companies Limited
INDUSTRY
Solae, LLC
INDUSTRY
Unilever R&D
INDUSTRY
University of Toronto
OTHER