Intermittent Preventive Treatment (IPTp) Versus Rapid Diagnostic Testing (RDT) and Treatment of Malaria in Pregnancy

PHASE3CompletedINTERVENTIONAL
Enrollment

3,333

Participants

Timeline

Start Date

February 28, 2007

Primary Completion Date

February 28, 2009

Study Completion Date

September 30, 2009

Conditions
MalariaAnaemiaPregnancy
Interventions
DRUG

Amodiaquine plus artesunate combination; sulphadoxine-pyrimethamine

"Eligible women will be allocated randomly to one of three groups and treated as follows:~Arm 1 (OptiMAL® antigen screening and treatment with SP plus LLIN group) - a woman in this will receive 1500mg/75mg (S/P) administered at the ANC as single dose on enrollment if her screening test is positive.~Arm 2 (OptiMAL® antigen screening and treatment with AQ+AS plus LLIN) - a woman in this will receive 300mg of AQ and 100mg co-administered two times a day for 3 days if her screening test is positive. The first dose is observed on enrolment day at the ANC.~Arm 3 (SP-IPTp plus LLIN group) - a woman in this will receive 1500mg/75mg (S/P) administered at the ANC as single dose on enrollment as recommended by national policy.~All enrolled women will be given one long lasting insecticide treated bed net each for use."

Trial Locations (1)

Unknown

Juaben Government Hospital, Juaben

All Listed Sponsors
collaborator

Kwame Nkrumah University of Science and Technology

OTHER

lead

London School of Hygiene and Tropical Medicine

OTHER

NCT00432367 - Intermittent Preventive Treatment (IPTp) Versus Rapid Diagnostic Testing (RDT) and Treatment of Malaria in Pregnancy | Biotech Hunter | Biotech Hunter