3,333
Participants
Start Date
February 28, 2007
Primary Completion Date
February 28, 2009
Study Completion Date
September 30, 2009
Amodiaquine plus artesunate combination; sulphadoxine-pyrimethamine
"Eligible women will be allocated randomly to one of three groups and treated as follows:~Arm 1 (OptiMAL® antigen screening and treatment with SP plus LLIN group) - a woman in this will receive 1500mg/75mg (S/P) administered at the ANC as single dose on enrollment if her screening test is positive.~Arm 2 (OptiMAL® antigen screening and treatment with AQ+AS plus LLIN) - a woman in this will receive 300mg of AQ and 100mg co-administered two times a day for 3 days if her screening test is positive. The first dose is observed on enrolment day at the ANC.~Arm 3 (SP-IPTp plus LLIN group) - a woman in this will receive 1500mg/75mg (S/P) administered at the ANC as single dose on enrollment as recommended by national policy.~All enrolled women will be given one long lasting insecticide treated bed net each for use."
Juaben Government Hospital, Juaben
Kwame Nkrumah University of Science and Technology
OTHER
London School of Hygiene and Tropical Medicine
OTHER