Effect of Azithromycin on Lung Function in 6-18 Year-olds With Cystic Fibrosis (CF) Not Infected With P. Aeruginosa

PHASE4CompletedINTERVENTIONAL
Enrollment

263

Participants

Timeline

Start Date

February 28, 2007

Primary Completion Date

July 31, 2009

Study Completion Date

November 30, 2009

Conditions
Cystic Fibrosis
Interventions
DRUG

azithromycin 250 mg tablets

"* One (1) tablet three times weekly for patients who weigh 40-79 lbs~* Two (2) tablets three times weekly for patients who weigh greater than or equal to 80 lbs"

DRUG

placebo tablets

"* One (1) tablet three times weekly for patients who weigh 40-79 lbs~* Two (2) tablets three times weekly for patients who weigh greater than or equal to 80 lbs"

Trial Locations (40)

10032

Columbia University, New York

10595

New York Medical College, Valhalla

13210

SUNY Upstate Medical University, Syracuse

14642

University of Rochester Medical Center, Rochester

15213

Children's Hospital of Pittsburgh, Pulmonary Medicine, Allergy & Immunology, Pittsburgh

19104

The Children's Hospital of Philadelphia, Philadelphia

19134

St. Christopher's Hospital for Children, Philadelphia

22908

University of Virginia at Charlottesville Children's Hospital, Charlottesville

26506

West Virginia University, Morgantown

27599

UNC Chapel Hill, Chapel Hill

30322

Emory University, Atlanta

37232

Vanderbilt Children's Hospital, Nashville

37916

East Tennessee Children's Hospital, Pediatric Pulmonary & Respiratory Care, Knoxville

38105

University of Tennessee Health Science Center, Memphis

40536

University of Kentucky, Lexington

43205

Nationwide Children's Hospital, Columbus

45229

Cincinnati Children's Hospital, Cincinnati

46202

Riley Hospital for Children, Indianapolis

48109

University of Michigan, Ann Arbor

53226

Children's Hospital of Wisconsin, Milwaukee

55455

University of Minnesota, Minneapolis

60614

Children's Memorial Hospital, Chicago

63110

Washington University, St Louis

64108

Children's Mercy Hospital, Kansas City

68198

University of Nebraska Medical Center - Pediatric Pulmonary, Omaha

84108

University of Utah Pediatric Pulmonology, Salt Lake City

85016

Phoenix Children's Hospital, Phoenix

06106

Connecticut Children's Medical Center, Hartford

02115

Children's Hospital Boston, Boston

03756

Dartmouth Hitchcock Medical Center, Lebanon

05401

Vermont Children's Hospital, Burlington

T3B 6A8

Alberta Children's Hospital, Calgary

V6H 3V4

BC Children's Hospital, Vancouver

A1B 3V6

Janeway Children's Health & Rehabilitation Hospital, St. John's

L8N 3Z5

McMaster Health Sciences Centre, Hamilton

N6A 5B8

Bryan Lyttle, MD, Private Practice, London

K1H 8L1

Children's Hospital of Eastern Ontario, Ottawa

M5G 1X8

The Hospital for Sick Children, Toronto

G7H 5H6

CSSS de Chicoutimi, Chicoutimi

H3H 1P3

Montreal Children's Hospital, Montreal

All Listed Sponsors
collaborator

Cystic Fibrosis Foundation

OTHER

lead

CF Therapeutics Development Network Coordinating Center

NETWORK

NCT00431964 - Effect of Azithromycin on Lung Function in 6-18 Year-olds With Cystic Fibrosis (CF) Not Infected With P. Aeruginosa | Biotech Hunter | Biotech Hunter