A Study Of Sunitinib Compared To Placebo For Patients With Advanced Pancreatic Islet Cell Tumors

PHASE3TerminatedINTERVENTIONAL
Enrollment

171

Participants

Timeline

Start Date

June 30, 2007

Primary Completion Date

April 30, 2009

Study Completion Date

April 30, 2009

Conditions
Carcinoma, Islet CellCarcinoma, Pancreas
Interventions
DRUG

sunitinib malate

"* sunitinib malate oral starting dose 37.5 mg daily (continuous dosing).~* Dose may be decreased to 25 mg daily in case of adverse events.~* It may be increased to 50 mg daily if no response is seen after 8 weeks on treatment.~* Dosing to continue until unacceptable toxicity, progression of disease, death, or study termination."

DRUG

Placebo

Placebo to match sunitinib taken daily (oral) on the same schedule as active agent below.

Trial Locations (54)

100

Pfizer Investigational Site, Taipei

333

Pfizer Investigational Site, Kwei-Shan

1070

Pfizer Investigational Site, Brussels

1200

Pfizer Investigational Site, Brussels

3000

Pfizer Investigational Site, Leuven

6000

Pfizer Investigational Site, Perth

13353

Pfizer Investigational Site, Berlin

13385

Pfizer Investigational Site, Marseille

20089

Pfizer Investigational Site, Rozzano (MI)

20141

Pfizer Investigational Site, Milan

23510

Pfizer Investigational Site, Norfolk

23538

Pfizer Investigational Site, Lübeck

26100

Pfizer Investigational Site, Cremona

28007

Pfizer Investigational Site, Madrid

28041

Pfizer Investigational Site, Madrid

28046

Pfizer Investigational Site, Madrid

33000

Pfizer Investigational Site, Bordeaux

35043

Pfizer Investigational Site, Marburg

35062

Pfizer Investigational Site, Rennes

52242

Pfizer Investigational Site, Iowa City

63110

Pfizer Investigational Site, St Louis

63141

Pfizer Investigational Site, Creve Coeur

63376

Pfizer Investigational Site, City of Saint Peters

69003

Pfizer Investigational Site, Lyon

69120

Pfizer Investigational Site, Heidelberg

75571

Pfizer Investigational Site, Paris

75679

Pfizer Investigational Site, Paris

78626

Pfizer Investigational Site, Georgetown

78705

Pfizer Investigational Site, Austin

78745

Pfizer Investigational Site, Austin

78758

Pfizer Investigational Site, Austin

78759

Pfizer Investigational Site, Austin

80045

Pfizer Investigational Site, Aurora

89081

Pfizer Investigational Site, Ulm

92118

Pfizer Investigational Site, Clichy

99437

Pfizer Investigational Site, Bad Berka

01605

Pfizer Investigational Site, Worcester

01655

Pfizer Investigational Site, Worcester

63110-1094

Pfizer Investigational Site, St Louis

V5Z 4E6

Pfizer Investigational Site, Vancouver

B3H 1V7

Pfizer Investigational Site, Halifax

B3H 2Y9

Pfizer Investigational Site, Halifax

B3H 3A7

Pfizer Investigational Site, Halifax

M5G 2M9

Pfizer Investigational Site, Toronto

H2X 3J4

Pfizer Investigational Site, Montreal

H3A 1A1

Pfizer Investigational Site, Montreal

H3T 1E2

Pfizer Investigational Site, Montreal

110-744

Pfizer Investigational Site, Seoul

138-736

Pfizer Investigational Site, Seoul

08025

Pfizer Investigational Site, Barcelona

08035

Pfizer Investigational Site, Barcelona

LS9 7TF

Pfizer Investigational Site, Leeds

L69 3GA

Pfizer Investigational Site, Liverpool

M20 4BX

Pfizer Investigational Site, Manchester

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY