Capecitabine and Oxaliplatin or Standard Follow-Up Care in Treating Patients Who Have Undergone Surgery for Locally Advanced Rectal Cancer

PHASE3CompletedINTERVENTIONAL
Enrollment

800

Participants

Timeline

Start Date

November 30, 2004

Primary Completion Date

March 31, 2008

Conditions
Colorectal Cancer
Interventions
DRUG

capecitabine

DRUG

oxaliplatin

PROCEDURE

adjuvant therapy

PROCEDURE

standard follow-up care

Trial Locations (72)

NE63 9JJ

Wansbeck General Hospital, Ashington

EX31 4JB

North Devon District Hospital, Barnstaple

LA14 4LF

Furness General Hospital, Barrow in Furness

B15 2TH

Queen Elizabeth Hospital at University Hospital of Birmingham NHS Trust, Birmingham

B75 7RR

Good Hope Hospital, Birmingham

B9 5SS

Birmingham Heartlands Hospital, Birmingham

FY3 8NR

Blackpool Victoria Hospital, Blackpool

PE21 9QT

Pilgrim Hospital, Boston

BS2 8ED

Bristol Haematology and Oncology Centre, Bristol

DE13 0RB

Queen's Hospital, Burton-on-Trent

CA2 7HY

Cumberland Infirmary, Carlisle

CM1 7ET

Broomfield Hospital, Chelmsford, Essex

GL53 7AN

Gloucestershire Oncology Centre at Cheltenham General Hospital, Cheltenham

HU16 5JQ

Castle Hill Hospital, Cottingham

CV2 2DX

Walsgrave Hospital, Coventry

DE1 2QY

Derbyshire Royal Infirmary, Derby

DN2 5LT

Doncaster Royal Infirmary, Doncaster

DH1 5TW

University Hospital of North Durham, Durham

CM20 1QX

Princess Alexandra Hospital, Essex

EX2 5DW

Royal Devon and Exeter Hospital, Exeter

BL4 0JR

Royal Bolton Hospital, Farnworth

NE9 6SX

Queen Elizabeth Hospital, Gateshead

GL1 3NN

Gloucestershire Royal Hospital, Gloucester

GU2 7XX

St. Luke's Cancer Centre at Royal Surrey County Hospital, Guildford

Unknown

Wycombe General Hospital, High Wycombe

HU8 9HE

Princess Royal Hospital at Hull and East Yorkshire NHS Trust, Hull

IG3 8YB

King George Hospital, Ilford, Essex

IP4 5PD

Ipswich Hospital, Ipswich

TW7 6AF

West Middlesex University Hospital, Isleworth

DY11 6RJ

Kidderminster Hospital, Kidderminster Worcestershire

WN1 2NN

Royal Albert Edward Infirmary, Lancanshire

LA1 4RP

Royal Lancaster Infirmary, Lancaster

LS16 6QB

Cookridge Hospital, Leeds

LN2 5QY

Lincoln County Hospital, Lincoln

L9 7AL

Aintree University Hospital, Liverpool

EC1A 7BE

Saint Bartholomew's Hospital, London

N18 1QX

Helen Rollason Cancer Care Centre at North Middlesex Hospital, London

N19 5NF

Whittington Hospital, London

NW1 2PG

University College of London Hospitals, London

NW1 2QG

UCL Cancer Institute, London

SW17 0QT

St. George's Hospital, London

W6 8RF

Charing Cross Hospital, London

SK10 3BL

Macclesfield District General Hospital, Macclesfield

M20 4BX

Christie Hospital, Manchester

CH63 4JY

Clatterbridge Centre for Oncology, Merseyside

TS4 3BW

James Cook University Hospital, Middlesbrough

PO30 5TG

St. Mary's Hospital, Newport

NN1 5BD

Northampton General Hospital, Northampton

HA6 2RN

Mount Vernon Cancer Centre at Mount Vernon Hospital, Northwood

OX3 7LJ

Churchill Hospital, Oxford

PR2 9HT

Rosemere Cancer Centre at Royal Preston Hospital, Preston

RM7 OBE

Oldchurch Hospital, Romford

M6 8HD

Hope Hospital, Salford

DN15 7BH

Scunthorpe General Hospital, Scunthorpe

S10 2SJ

Cancer Research Centre at Weston Park Hospital, Sheffield

SY3 8XQ

Royal Shrewsbury Hospital, Shrewsbury

SO16 6YD

Southampton General Hospital, Southampton

PR8 6PN

Southport and Formby District General Hospital, Southport

SR4 7TP

Sunderland Royal Hospital, Sunderland

KT2 7QB

Kingston Hospital, Surrey

WS2 9PS

Walsall Manor Hospital, Walsall

B71 4HJ

Sandwell General Hospital, West Bromwich

SS0 0RY

Southend University Hospital NHS Foundation Trust, Westcliff-on-Sea

WR5 1DD

Worcester Royal Hospital, Worcester

BA21 4AT

Yeovil District Hospital, Yeovil

AB25 2ZN

Aberdeen Royal Infirmary, Aberdeen

EH4 2XU

Edinburgh Cancer Centre at Western General Hospital, Edinburgh

G11 6NT

Beatson West of Scotland Cancer Centre, Glasgow

CF14 2TL

Velindre Cancer Center at Velindre Hospital, Cardiff

CF72 8XR

Royal Glamorgan Hospital, Lhantrisant

HR1 2ER

Hereford Hospitals, Hereford

YO12 6QL

Scarborough General Hospital, Scarborough

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Cancer Research UK

OTHER