48
Participants
Start Date
January 19, 2007
Primary Completion Date
November 1, 2019
Study Completion Date
November 1, 2019
Campath 1H
Conditioning with Campath 1 mg/kg total dose given intravenously over 5 days
Busulfan
Busulfan 5-10 mg/kg total dose given intravenously over 2 days based on patient underlining immune deficiency disorder
Horse Anti-human Thymocyte Globulin (h-ATG)
Conditioning with h-ATG 40 mg/kg total dose over 4 days given intravenously
Total Body Irradiation (TBI)
TBI 200 - 300 centigray (cGy) in two fractions at day -2 or same day depending on patient underlining immune deficiency disorder
Sirolimus or equivalent based on response
post Transplantation immunosuppressants
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda
National Institute of Allergy and Infectious Diseases (NIAID)
NIH