Effects of Intensive Long-Term Vasodilation in Hypertensive Patients With Microvascular Angina Pectoris

NATerminatedINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

January 31, 2007

Primary Completion Date

December 31, 2008

Study Completion Date

December 31, 2008

Conditions
Microvascular AnginaHypertension
Interventions
DRUG

Lercanidipine

Individual titration, max. dose 20 mg OD for 8 months

DRUG

Valsartan

Individual titration, max. dose 160 mg OD for 8 months

DRUG

Nicorandil

Individual titration, max. dose 20 mg BD for 8 months

DRUG

Doxazosin

Individual titration, max. dose 4 mg OD for 8 months

DRUG

Moxonidin

Possible add-on therapy in case target blood pressure can not be reached with a combination of the other drugs in the Vasodilatory arm. Individual titration, max. dose 0,2 mg OD for 8 months

DRUG

Pindolol

Possible add-on therapy in case target blood pressure can not be reached with a combination of the other drugs in the Vasodilatory arm. Individual titration, max. dose 10 mg OD for 8 months

DRUG

Amiloride, hydrochlorothiazide

Possible add-on therapy in case target blood pressure can not be reached with a combination of the other drugs in the Vasodilatory arm. Individual titration, max. dose 1 tbl. OD for 8 months

Trial Locations (1)

8000

Aarhus Hospital, Aarhus

Sponsors
All Listed Sponsors
collaborator

Danish Cardiovascular Research Academy

UNKNOWN

collaborator

Danish Heart Foundation

OTHER

collaborator

Novartis

INDUSTRY

lead

University of Aarhus

OTHER