Effect of Etomidate on Hemodynamics and Adrenocortical Function After Cardiac Surgery

PHASE4CompletedINTERVENTIONAL
Enrollment

130

Participants

Timeline

Start Date

November 30, 2006

Primary Completion Date

December 31, 2009

Study Completion Date

December 31, 2009

Conditions
Coronary Artery DiseaseMitral Valve Regurgitation
Interventions
DRUG

Etomidate

Single induction dose of etomidate 0.2%; total dose 0.15 mg/kg

DRUG

Propofol

Single induction dose of propofol 2%; total dose 1.5 mg/kg

DRUG

Hydrocortisone

Hydrocortisone 100 mg/2 ml: day of operation 3x, POD 1 2x, POD 2 1x

DRUG

NaCl 0.9%

NaCl 0.9% 2 ml; day of operation 3x, POD 1 2x, POD 2 1x

OTHER

Tetracosactin

Diagnostic test, Tetracosactin 250 microg iv

Trial Locations (1)

3010

Departments of Intensive Care Medicine and Anesthesiology, Bern

All Listed Sponsors
lead

Insel Gruppe AG, University Hospital Bern

OTHER

NCT00415701 - Effect of Etomidate on Hemodynamics and Adrenocortical Function After Cardiac Surgery | Biotech Hunter | Biotech Hunter