Antihypertensive Treatment in Acute Cerebral Hemorrhage

PHASE1CompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

July 31, 2005

Primary Completion Date

September 30, 2007

Study Completion Date

March 31, 2008

Conditions
Intracerebral HemorrhageHypertensionStroke
Interventions
DRUG

nicardipine

"Intravenous (IV) nicardipine infusion. It is expected that the treatment duration will vary between 18 and 24 hours.~* Started at 5mg/h~* Titrated by 2.5mg/hour every 15 minutes to bring systolic blood pressure in target range for the applicable Tier. Max dose 15mg/hour \*Once target systolic blood pressure reached, dose decreased by 2.5mg/hour every 15 minutes until systolic blood pressure maintained in the target range or the medication is discontinued."

Trial Locations (12)

10032

Columbia University Medical Center, New York

29425

Statistical Coordinating Center: Medical University of South Carolina, Charleston

43210

Ohio State University, Columbus

44106

Case Western Reserve University, Cleveland

55455

Clinical Coordinating Center: University of Minnesota, Fairview Hospital, Minneapolis

63108

Saint Louis University, St Louis

66160

Kansas University Medical Center, Kansas City

The University of Kansas School of Medicine, Wichita Via Christi Regional Medical Center, Kansas City

90033

University of Southern California, Los Angeles

02115

Massachusetts General/Brigham Women's Hospital, Boston

08818

JFK Medical Center, Edison

07107

University of Medicine and Dentistry of New Jersey, Newark

All Listed Sponsors
collaborator

National Institute of Neurological Disorders and Stroke (NINDS)

NIH

lead

University of Minnesota

OTHER

NCT00415610 - Antihypertensive Treatment in Acute Cerebral Hemorrhage | Biotech Hunter | Biotech Hunter