AMENO-2: Aprepitant Plus Palonosetron Versus Granisetron in the Prevention of Nausea and the Emesis Induced by Chemotherapy in Patients Treated With Haematopoietic Progenitors

PHASE4CompletedINTERVENTIONAL
Enrollment

196

Participants

Timeline

Start Date

November 30, 2006

Primary Completion Date

September 30, 2009

Study Completion Date

September 30, 2009

Conditions
LeukemiaLymphoma
Interventions
DRUG

Aprepitant

Aprepitant: 125 mg oral day 1, follows by 80 mg oral every 24 hours in next days

DRUG

Palonosetron

Palonosetrón: 0.25 mg iv every 48 hours, starting day 1

DRUG

Granisetron

Granisetrón : 3 mg iv day, all days the patient will be treated with chemotherapy, and Aprepitant placebo 125 mg oral, day 1, and 80 mg next days in chemotherapy treatment

Trial Locations (5)

Unknown

Hospital Universitario Gregorio Marañón, Madrid

Hospital Universitario La Paz, Madrid

Hospital Universitario la Princesa, Madrid

Hospital Clínico Universitario de Salamanca, Salamanca

Hospital Universitario Marqués de Valdecilla, Santander

All Listed Sponsors
collaborator

Merck Sharp & Dohme LLC

INDUSTRY

lead

PETHEMA Foundation

OTHER

NCT00415103 - AMENO-2: Aprepitant Plus Palonosetron Versus Granisetron in the Prevention of Nausea and the Emesis Induced by Chemotherapy in Patients Treated With Haematopoietic Progenitors | Biotech Hunter | Biotech Hunter