Effects of Nefopam on Hyperalgesia After Cardiac Surgery

PHASE2/PHASE3CompletedINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

December 31, 2006

Primary Completion Date

December 31, 2007

Study Completion Date

November 30, 2008

Conditions
HyperalgesiaPain, PostoperativePain, Chronic Disease
Interventions
DRUG

Nefopam

0,3mg/kg IV bolus preoperative and 65 µg/kg/h during H48 postoperative

DRUG

néfopam

bolus Néfopam (0,3mg/kg) during 10 min at the end of surgery and 65 µg/kg/h during postoperative H48

DRUG

Placebo comparator

bolus NaCl during 10 min at the end of surgery and during postoperative H48

Trial Locations (1)

33604

Département d'Anesthésie-Réanimation II - Hôpital cardiologique - Groupe Hospitalier Sud, CHU de Bordeaux - 4, Av de Magellan, Pessac

All Listed Sponsors
lead

University Hospital, Bordeaux

OTHER

NCT00413257 - Effects of Nefopam on Hyperalgesia After Cardiac Surgery | Biotech Hunter | Biotech Hunter