Combined Vasopressin, Methylprednisolone, and Epinephrine for Inhospital Cardiac Arrest

PHASE2CompletedINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

June 30, 2006

Primary Completion Date

April 30, 2007

Study Completion Date

April 30, 2007

Conditions
Heart Arrest
Interventions
DRUG

Vasopressin, Epinephrine, and Steroids

During resuscitation, study group patients receive vasopresssin \[20 IU IV maximum dose = 100 IU\] and methylprednisolone (40 mg IV). Epinephrine is given to both groups according to guidelines for resuscitation 2005. In the study group, postresuscitation shock is treated with stress-dose hydrocortisone.

DRUG

Placebo, Epinephrine, Placebo

Epinephrine is given to both groups according to guidelines for resuscitation 2005. Control group patients receive placebo instead of vasopressin and steroids.

Trial Locations (1)

106 75

Evaggelismos General Hospital, Athens

All Listed Sponsors
lead

University of Athens

OTHER

NCT00411879 - Combined Vasopressin, Methylprednisolone, and Epinephrine for Inhospital Cardiac Arrest | Biotech Hunter | Biotech Hunter