Prophylactic Use of Maribavir for the Prevention of Cytomegalovirus (CMV) Disease in Stem Cell Transplant Recipients

PHASE3CompletedINTERVENTIONAL
Enrollment

681

Participants

Timeline

Start Date

December 13, 2006

Primary Completion Date

November 10, 2008

Study Completion Date

May 23, 2009

Conditions
Cytomegalovirus Infections
Interventions
DRUG

maribavir

100 mg twice daily for up to 12 weeks

OTHER

placebo

twice daily for up to 12 weeks

Trial Locations (97)

1200

Cliniques Universitaires St,Luc Dept Hematology, Brussels

2060

ZNA Stuivenberg, Antwerp

3000

UZ Gasthuisberg, Leuven

4000

CHU Sart -Tilman Department of Medicine, Hematology, Liège

8000

AZ Sint Jan, Department of Hematology, Bruges

10021

Memorial Sloan-Kettering Cancer Center, New York

New York Presbyterian Hospital,Weill Cornell Medical Center, New York

10029

Mount Sinai Hospital, New York

13273

Institut Paoli Calmettes, Marseille

14186

Karolinska University Hospital, Huddinge

14263

Roswell Park Cancer Institute, Buffalo

14642

University of Rochester Medical Center, Rochester

15224

Western Pennsylvania Cancer Institute, Pittsburgh

15232

University of Pittsburgh Cancer Institute, Pittsburgh

16132

University of San Martino Hospital, Genova

17033

Penn State Milton S. Hershey Medical Center, Hershey

19107

Thomas Jefferson, Philadelphia

19111

Jeanes Hospital - Temple, Philadelphia

20132

San Raffaele del Monte Tabor, Milan

20246

University of Hamburg-Eppendorf, Hamburg

23298

Medical College of Virginia, Richmond

27157

Wake Forest Medical Center, Winston-Salem

27599

University of North Carolina Hospital, Chapel Hill

27710

Duke Medical Center, Durham

30322

Emory University, Atlanta

30625

Hannover, Medizinische Hochschule, Hanover

32610

Shands Hospital, Gainesville

33600

Hopital Haut-Leveque, Pessac

33612

H. Lee Moffitt Cancer Center, Tampa

37232

Vanderbilt Medical Center, Nashville

40202

University Medical Center University of Louisville Hospital, Louisville

40536

University of Kentucky Chandler Medical Center, Lexington

44093

Hopital Hotel Dieu, Nantes

44106

Ireland Cancer Center Case Western Reserve University, Cleveland

45122

University of Essen, Essen

45236

The Jewish Hospital, Cincinnati

46107

St Francis Hospital, Beech Grove

48201

Wayne State Medical Center, Detroit

48202

Henry Ford Health System, Detroit

50134

Careggi University Hospital, Florence

50937

Universitaetsklinikum Koeln, Clinic I for internal Medicine, Cologne

52242

University of Iowa Hospitals and Clinics, Iowa City

55131

Johannes-Gutenberg University, Mainz

55455

University of Minnesota, Minneapolis

55905

Mayo Clinic College of Medicine, Rochester

60153

Loyola University, Maywood

60611

Northwestern University Medical Center, Chicago

60637

University of Chicago, Chicago

63110

Washington University School of Medicine, St Louis

65123

Pescara Hospital, Pescara

69120

University of Heidelberg, Heidelberg

69437

Edouard Herriot Hopital, Lyon

72205

University of Arkansas Myeloma Institute, Little Rock

73104

University of Oklahoma, Oklahoma City

75246

Baylor University Medical Center, Dallas

75475

Hopital St. Louis, Paris

77030

Methodist Hospital, Houston

78229

Texas Transplant Institute, San Antonio

79106

University of Freiburg, Freiburg im Breisgau

80218

Rocky Mountain Cancer Center, Denver

84103

Latter Day Saints Hospital, Salt Lake City

89081

University Clinic of Ulm, Ulm

89100

Bianchi-Melacrino-Morelli Hospital, Reggio Calabria

91010

City of Hope Medical Center, Duarte

92037

Scripps Green Hospital, La Jolla

94010

Hopital Henri Mondor, Créteil

94143

University of California, San Francisco, San Francisco

94305

Stanford University Medical Center, Stanford

98108

VA Puget Sound Health Center, Seattle

98109

Fred Hutchinson Cancer Research Center, Seattle

92093-0960

UCSD Moores Center, La Jolla

90095-1678

UCLA Medical Center, Los Angeles

21201-1595

Greenbaum Cancer Center, Baltimore

02114

Massachusettes General, Boston

02115

Brigham and Women's Hospital, Boston

02215

Beth Israel Deaconess Medical Center, Boston

48109-0914

University of Michigan, Ann Arbor

07601

Hackensack University Medical Center, Hackensack

97239-3098

Oregon Health and Sciences University, Portland

77030-4009

MD Anderson Cancer Center, Houston

26506-9162

West Virginia University Hospital, Morgantown

B3H2Y9

QEII Health Sciences Center, Halifax

L8N 3Z5

McMaster University Medical Center, Hamilton

N6A 4G5

London Health Sciences Centre, London

K1H 8L6

Ottawa General Campus, Ottawa

G1J 1Z4

Hopital l'Enfant Jesus, Québec

01307

Univ. Clinic Dresden, Dresden

University Clinic of Dresden, Dresden

08036

Barcelona Hospital, Barcelona

08907

Duran i Reynals Hospital, Barcelona

E-37007

University of Salamanca, Salamanca

S-413 45

Sahlgrenska University Hospital, Gothenburg

141 86

Karolinska University Hospital,Huddinge, Stockholm

751 85

Akademiska Sjukhuset, Dept Hematology, Uppsala

NW1 2BU

University College Hospital, London

NW3 2QG

Royal Free Hospital, London

W12 OHS

Hammersmith Hospital, London

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Shire

INDUSTRY

NCT00411645 - Prophylactic Use of Maribavir for the Prevention of Cytomegalovirus (CMV) Disease in Stem Cell Transplant Recipients | Biotech Hunter | Biotech Hunter