Randomized Intervention for Children With Vesicoureteral Reflux (RIVUR)

PHASE3CompletedINTERVENTIONAL
Enrollment

607

Participants

Timeline

Start Date

May 31, 2007

Primary Completion Date

June 30, 2013

Study Completion Date

May 31, 2014

Conditions
Vesicoureteral RefluxUrinary Tract Infections
Interventions
DRUG

Trimethoprim-Sulfamethoxazole

Cherry-flavored liquid suspension with 3 mg of trimethoprim plus 15 mg sulfamethoxazole per kilogram of body weight, taken once daily.

DRUG

Placebo

Cherry flavored liquid suspension matched to active comparator.

Trial Locations (19)

14222

Women and Children's Hospital of Buffalo, Buffalo

15213

Children's Hospital of Pittsburgh, Pittsburgh

17033

Penn State Hershey Medical Center, Hershey

19104

Children's Hospital of Philadelphia, Philadelphia

19803

Alfred I. duPont Hospital for Children, Wilmington

20010

Children's National Medical Center, Washington D.C.

21287

Johns Hopkins School of Medicine, Baltimore

27157

Wake Forest University Baptist Medical Center, Winston-Salem

35233

University of Alabama, Birmingham

44308

Akron Children's Hospital, Akron

45229

Cincinnati Children's Hospital, Cincinnati

48201

Children's Hospital of Michigan, Detroit

53792

University of Wisconsin Children's Hospital, Madison

60614

Ann & Robert Lurie Children's Hospital of Chicago, Chicago

64108

Children's Mercy Hospital, Kansas City

73104

University of Oklahoma, Oklahoma City

77030

Texas Children's Hospital, Houston

97239

Oregon Health & Science University, Portland

02115

Children's Hospital of Boston, Boston

All Listed Sponsors
collaborator

University of North Carolina, Chapel Hill

OTHER

lead

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

NCT00405704 - Randomized Intervention for Children With Vesicoureteral Reflux (RIVUR) | Biotech Hunter | Biotech Hunter