11
Participants
Start Date
November 30, 2007
Primary Completion Date
July 31, 2011
Study Completion Date
November 30, 2013
Bevacizumab
15 mg/kg on day 1 of each of 6 cycles
Rituximab
"Rituximab will be administered prior to CHOP on day 3 of every cycle for a total of 6 cycles.~The dose to be administered is:~Rituximab: 375 mg/m2"
CHOP
Standard CHOP chemotherapy will be administered at full dose every 21 days for a total of 6 cycles. The doses to be used are: Cyclophosphamide: 750 mg/m2 IV on day 3 Doxorubicin: 50 mg/m2 IV on day 3 Vincristine: 1.4 mg/m2 IV (not to exceed 2.0 mg total) on day 3 Prednisone: 100 mg PO days 3 - 7
Weill Medical College of Cornell University, New York
Rush University Medical Center, Chicago
Weill Medical College of Cornell University
OTHER